Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contact rapide
Veuillez m'envoyer plus d'informations sur
Fmoc-Dbz(o-Boc)-OH
Nom chimique: 3-(Fmoc-amino)-4-(Boc-amino)-benzoic acid // Synonymes: 4-tert-Butoxycarbonylamino-3-(9H-fluoren-9-ylmethoxycarbonylamino)-benzoic acid, 3-Fmoc-4-Boc-diaminobenzoic acid
- n° Art.:FAA3167
- n° CAS:1823479-63-5
- Formule:C27H26N2O6
- Masse moléculaire:474,51 g/mol
Starting at 300,00 €
description
Typically, 3,4-diaminobenzoid acid (Dbz) is used for the efficient synthesis of peptide thioesters by Fmoc chemistry solid phase peptide synthesis. Optionally, a solubility tag can be attached to the C-terminus. Protection of the free amine is required to prevent over-acylation observed using the typical Dawson reagent. In addition, Boc-protection of the ortho-amine prevents formation of undesired side-products, e.g. benzimidazolinone formation, which might be observed for other types of protecting groups.
references
Benzimidazolinone-Free Peptide o-Aminoanilides for Chemical Protein Synthesis; J. Mannuthodikayil, S. Singh, A. Biswas, A. Kar, W. Tabassum, P. Vydyam, M. K. Bhattacharyya, and K. Mandal; Org. Lett. 2019; 21: 9040-9044. https://doi.org/10.1021/acs.orglett.9b03440.
Commande groupée?
Vous avez besoin de plus grandes quantités pour votre développement ou production?
Besoin d'informations supplémentaires sur ce produit?
entrer en contact
Related Products
Brochures et dépliants
Des produits qui pourraient également vous intéresser!
