Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contact rapide
Veuillez m'envoyer plus d'informations sur
COMU ®
Nom chimique: 1-[1-(Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino]-uronium hexafluorophosphate
- n° Art.:RL-1175
- n° CAS:1075198-30-9
- Formule:C12H19N4O4PF6
- Masse moléculaire:428,26 g/mol
description
COMU is an efficient coupling reagent requiring one equivalent of base during bond formation as it liberates morpholine. Typical applications are amide bond formation, eg. in both solution and solid phase synthesis at room temperature or with conventional heating or microwave. Minimized racemization. Supposed to be non-allergenic. Couplings can be monitored visually or colourimetrically due to color change from yellow to orange; the reagent shows excellent solubility in DMF and NMP.
references
R. Subirós-Funosas, R. Prohens, R. Barbas, A. El-Faham, F. Albericio; Chem. Eur. J. 2009; 15: 9394-9403.
A. El-Faham, F. Albericio; J. Pept. Sci. 2010; 16: 6-9.
R. Subiros-Funosas, S. N. Khattab, L. Nieto-Rodriguez, A. El-Faham, F. Albericio; Aldrichim. Acta 2013; 46: 21-40.
A. El-Faham, R. S. Funosas, R. Prohens, F. Albericio; Chem. Eur. J. 2009; 15: 9404-9416.
R. Subiros-Funosas, G. A. Acosta, A. El-Faham, F. Albericio; Tetrahedron Lett. 2009; 50: 6200-6202.
A. El-Faham and F. Albericio, J. Org. Chem. 2008; 73: 2731.
Commande groupée?
Vous avez besoin de plus grandes quantités pour votre développement ou production?
Besoin d'informations supplémentaires sur ce produit?
entrer en contact
Related Products
Des produits qui pourraient également vous intéresser!
