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Nom chimique: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-((7-nitrobenzo[c][1,2,5]thiadiazol-4-yl)amino)propanoic acid // Synonymes: Fmoc-L-Dap(nitrobenzothiodiazole)-OH, Fmoc-Dap(NBTD)-OH
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Benzodiazole amino acids are excellent small building blocks for the construction of background-free, non-invasive peptide probes for fluorescence imaging. This Fmoc derivative is suitable for solid-phase peptide synthesis.
Absorption maximum of the unprotected amino acid = 460 nm. Emission maximum of the unprotected amino acid = 546 nm.
Small Fluorogenic Amino Acids for Peptide-Guided Background-Free Imaging; F. de Moliner, Z. Konieczna, L. Mendive-Tapia, R. S. Saleeb, K. Morris, J. A. Gonzalez-Vera, T. Kaizuka, S. G. N. Grant, M. H. Horrocks, M. Vendrell; Angew. Chem. Int. Ed. 2023; 62: e202216231. https://doi.org/10.1002/anie.202216231
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